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  1. 01Kim U, Park MH, Kim DH, Yoo HH*, Metabolite Profiling of ginsenoside Re in rat urine and faeces after oral administration. Food Chemistry 136 (2013) 1364-1369
  2. 02Kim TK, Yoo HH, Kim EJ, Sa JH, Lee BY, Park JH. Comparative protein binding of taxotere and SID530, a new docetaxel formulation with hydroxypropyl-beta-cyclodextrin, in human plasma in vitro. Pharmazie. 2012 Sep;67(9): 789-91.
  3. 03Jin MJ, Lee J, In MK, Yoo HH*. Characterization of In Vitro Metabolites of CP 47,497, a Synthetic Cannabinoid, in Human Liver Microsomes by LC-MS/MS. J Forensic Sci. 2012 Aug 29. doi: 10.1111/j.1556-4029.2012.02261.x.
  4. 04Kim TK, Kim IS, Yoo HH*. Determination of docetaxel in rat plasma and its application in the comparative pharmacokinetics of Taxotere and SID530, a novel docetaxel formulation with hydroxypropyl-b-cyclodextrin. Biomed Chromatogr. 2012 Jul 27. doi: 10.1002/bmc. 2792.
  5. 05Islam MN, Kim U, Kim DH, Dong MS, Yoo HH*. High-performance liquid chromatography-based multivariate analysis to predict the estrogenic activity of an Epimedium koreanum extract. Biosci Biotechnol Biochem. 2012;76(5):923-7.
  6. 06Yoo HH, Park JH. Cyclooxygenase inhibitory activity of ginsenosides from heat-processed gin-seng. Food Chemistry 133 (2012)998-1000.
  7. 07Kim TK, Yoo HH, Park JH. Validated LC-MS/MS method for the determination of mirodenafil inrat plasma and its application to a comparative pharmacokinetic study of the free base and hydrochloride salt forms of mirodenafil. Arzneimittelforschung. 2012 Jul:62(7):351-4.
  8. 08Park JW, Bae H, Lee G, Hong BG, Yoo HH, Lim SJ, Lee K, Kim J, Ryu B, Lee BJ, Bae J, Lee H, Bu Y. Prophylactic effects of Lonicera Japonica extract on dextran sulphate sodium-induced colitis in a mouse model by the inhibition of the Th1/Th17 response. Br JNutr. 2012 May 9:1-10
  9. 09Kim TK, Yoo HH, Kim EJ, Lee BY, Park JH. Pharmacokinetic equivalence of Taxotere and SID530, a novel docetaxel formulation containing hydroxypropyl-beta-cyclodextrin in monkeys. Arzneimittelforschung. 2012 Jun;62(6);280-4.
  10. 10Kim U, Jin MJ, Lee J, Han SB, In MK, Yoo HH*. Tentative identification of phase I metabolites of HU-210, a classical synthetic cannabinoid, by LC-MS/MS. J Pharm Biomed Anal.2012 May;64-65:26-34
  11. 11Islam MN, Chung HJ, Kim DH, Yoo HH*. A simple isocratic HPLC method for the simultaneous determination of bioactive components of Scutellariae Radis extract. Nat Prod Res. 2012 Nov;26(21):1957-62
  12. 12Kang Ks, Kim Hy, Yoo HH, Piao XL, Ham J, Yang HO, Park JH. Protective effect of ginseng sapo-genins against 2,2’-azobis (1-aminopropane) dihydrochloride (AAPH)-induced LLC-PK₁ cell damage. Bioorg Med Chem Lett. 2012 Jan 1;22(1):634-7.
  13. 13Chung HJ, Lim S. Kim IS, Bu Y, Kim H, Kim DH, Yoo HH. Simultaneou Determination of Baica-lein, Baicalin, Wogonin, and Wogonoside in Rat Plasma by LC-MS/MS for Studying the Pharma-cokinetics of the Standardized Extract of Scutellariae Radix. Bull. Korean Chem. Soc. 2012,33(1)177-182.
  14. 14Lee SK, Kim DH, Yoo HH*. Comparative metabolism of sildenafil in liver microsomes of different species by using LC/MS-based multivariate analysis. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Oct 15;879(28);3005-11
  15. 15Lee KM, Kim HJ, Jeong ES, Yoo HH, Kwon OS, Jin C, Kim DH, Lee J. Simple and accurate quanti-tative analysis of seven prohibited threshold substances in human urine by liquid chromatogra-phy/tandem mass spectrometry in doping control. Rapid Commun Mass Spectrom. 2011 Aug30;25(16);2261-7.
  16. 16Jeon BW, Yoo HH, Jeong ES, Kim HJ, Jin C, Kim DH, Lee J. LC-ESI/MS/MS method for rapid screening and confirmation of 44 exogenous anabolic steroids in human urine. Anal Bioanal Chem. 2011 Sep;401(4):1353-63.
  17. 17Yoo HH, Kim NS, Kim MJ, Shin D, Shin JG, Kim DH. Enantioselective carbonyl reduction of eper-isone in human liver microsomes. Xenobiotica. 2011 Sep;41(9):758-63
  18. 18Jin MJ, Jin C, Kim JY, In MK, Kwon OS, Yoo HH*. A quantitative method for simultaneous deter-mination of 5-methoxy-N,N-diisopropyltryptamine and its metabolites in urine using liquid chromatography-electrospray ionization-tandem mass spectrometry. J Forensic Sci.2011 Jul;56(4)1044-8.
  19. 19Kim Y, Kim UY, In MK, Lee J, Kwon OS, Yoo HH*. Hydrophillic Interaction Chromatography-tan-dem Mass Spectrometry Method for Identification and Quantitation of 5-MeO-DIPT and its Metabolites in Rat Urine. Bull Korean Chem. Soc. 2011,32 (4), 1158-1164.
  20. 20Lee BJ, Jo IY, Bu Y, Park JW, Maeng S, Kang H, Jang W, Hwng DS, Lee W, Min K, Kim JI, Yoo HH, Lew JH. Iplatelet effects of Spatholobus suberectus via inhibition of the glycoprotein IIb/IIIa receptor. J Ethnopharmacol. 2011 Mar 24;134(2):460-7.
  21. 21Lee SK, Kim Sh, Kim HJ, Yoo HH, Kwon OS, In MK, Jin C, Kim DH, Lee J. Simultaneous qualita-tive and quantitative method using liquid chromatography selected reaction monitoring-trig-gerde quantitation-enhancde data-dependent tandem mass spectrometry for the identification and classification of amphetamine-type stimulant abusers in human urine. Rapid Commun Mass Spectrom. 2010 Nov 15;24(21):3139-45.
  22. 22Jin MJ, Kim U, Kim IS, Kim Y, Kim DH, Han SB, Kim DH, Kwon OS, Yoo HH*. Effects of Gut Micro-flora on Pharmacokinetics of Hesperidin: A Study in Conventional and Pseudo Germ-Free Rats. Journal of Toxicology and Environmental Health, Part A 2010;73(21-22):1441-50.
  23. 23MJ Kang, Hyeim Lee, SM Shin, HH Yoo, OS Kwon, C Jin. Performance Chracteristic of the β-Human Chorionic Gonadotropin Assay on the Access 2 for Its Use in Doping Control. Bull. Korean Chem. Soc. 2010; 31 (10): 1-4.
  24. 24MJ Kang, SM Shin, HH Yoo, OS Kwon, C Jin. Characteristics of IEF Patterns and SDS-PAGE Re-sults of Korea EPO Biosimilars. Bull. Korean Chem. Soc. 2010; 31 (9): 2493-2496.
  25. 25Lee SK, Kim Y, Jin C, Lee SH, Kang MJ, Jeong Tc, Jeong SY, Kim DH, Yoo HH*. Inhibitory Effects of Deoxypodophyllotoxin from Anthriscus sylvestris on Human CYP2C9 and CYP3A4. Planta Med. 2010; 76(7):701-4.
  26. 26Lee SK, kim DH, Jin C, Yoo HH*. Determination of Urinary Trimethylamine and Trimethylamine N-oxide by Liquid Chromatography-Tandem Mass Spectrometry Using Mixed-Mode Stationary Phases. Bull. Korean Chem. Soc. 2010; 31 (2): 483-486.
  27. 27Bhuiyan MI, Islam MN, Jung SY, Yoo HH, Lee YS, Jin C. Involvement of ceramide in ischemic tolerance induced by preconditioning with sublethal oxygen-glucose deprivation in primary cultured cortical neurons of rats. Biol Pharm Bull. 2010; 33(1):11-7.
  28. 28Islam MN, Nam JW, Lee J, Seo EK, Han SB, Kim DH, Jin C, Yoo HH*. A Validated LC Method for Simultaneous Determination of Phenolic, Coumarin and Phthalide Compounds in the Ethanolic Extract of Angelica tenuisima. Chromatographia 2009; 70: 1079-85.
  29. 29Lee SK, Kang MJ, Jin C, In MK, Kim DH, Yoo HH*. Flavin-containing monooxygenase 1-catalysed N, N-dimethylamphetamine N-oxidation. Xenobiotica. 2009; 39(9): 680-6.
  30. 30Chung HJ, Kim NS, Kim EJ, Kim TK, Ryu KH, Lee BY, Kim DH, Jin C, Yoo HH*. Negligible Effect of Ginkgo Biloba Extract on the Pharmacokinetics of Cilostazol. Biomolecules & Therapeutics, 17(3), 311-317 (2009).
  31. 31Islam MN, Yoo HH*, Sung CK, Dong MS, Park YI, Jin C, Kim DH. Simultaneous determination of phenolic acids and phthalide compounds by liquid chromatography for quality assessment of Rhizoma cnidii. J AOAC Int. 2009 Mar-Apr;92(2):375-81.
  32. 32Yoo HH*, Kim NS, Lee J, Sohn DR, Jin C, Kim DH. Characterization of human cytochrome P450 enzymes involved in the biotransformation of eperisone. Xenobiotica. 2009 Jan;39(1):1-10.
  33. 33Lee SK, Kim Y, Suh S, Suh Yj, In MK, Kim DH, Jin C, Yoo HH*. Detox agents do not affect the pharmacokinetics of methamphetamine in the rat. Forensic Sci Int. 2009 Apr 15;186(1-3):e21-4.
  34. 34Yoo HH, Yoon HJ, Shin HJ, Lee SH, Yoon HR. Characterization of Plasma Carnitine Level in Obese Adolescent Korean Women. Biomolecules & Therapeutics, 17(2), 181-187 (2009).
  35. 35Islam MN, Lee SK, Jeong SY, Kim DH, Jin C, Yoo HH*. Quantitative and Pattern Recognition Analyses for the Quality Evaluation of Herba Epimedii by HPLC. Bull. Korean Chem. Soc. 2009. Vol. 30, No. 1:137-144.
  36. 36Lee SK, Kim Y, Kim TK, Im GJ, Lee BY, Kim DH, Jin C, Yoo HH*. Determination of mirodenafil and sildenafil in the plasma and corpus cavernous of SD male rats. J Pharm Biomed Anal. 2009 Feb 20; 49(2):513-8.
  37. 37Islam MN, Yoo HH*, Lee J, Nam JW, Seo EK, Jin C, Kim DH. Simultaneous determination of bio-active xanthone glycosides and norlignans from ethanolic extract of Anemarrhena asphodeloi-des by liquid chromatography. J AOAC Int. 2008 Nov-Dec;91(6):1271-7.
  38. 38Kim JY, Cheong JC, Ko BJ, Lee SK, Yoo HH, Jin C, In MK. Simultaneous determination of meth-amphetamine, 3,4-methylenedioxy-N-methylamphetamine, 3,4-methylenedioxy-N-ethylam-phetamine, N,N-dimethylamphetamine, and their metabolites in urine by liquid chromatogram-phy-dlectrospray ionization-tandem mass spectrometry. Arch Pharm Res. 2008 Dec;31(12):1644-51.
  39. 39Lee SK, Lee DJ, Yoo HH, Kim JH, Seo YM, Shin S, Choi JH, Jeon TW, Kang MJ, Jeong TC. Identifi-cation of glutathione conjugates of 1-bromopentane and its hepatotoxicity in female BALB/c mice. Arch Pharm Res. 2008 Oct;31(10):1317-23
  40. 40Yoo HH*, Lee SK, Lim SY, Kim Y, Kang MJ, Kim EJ, Park YH, Im GJ, Lee BY, Kim DH. LC-MS/MS method for determination of hederacolchiside E, a neuroactive saponin from Pulsatilla Koreana extract in rat plasma for pharmacokinetic study. J Pharm Biomed Anal. 2008 Dec 15;48(5):1425-9.
  41. 41Yoo HH, Lee SH, Jin C, Kim DH. Mechanism-based inactivation of cytochrome p450 3A4 by methylenedioxyphenyl lignans from Acanthopanax chiisanensis. Planta Med. 2008 Jun;74(8):822-7.
  42. 42Yoo HH, Chung HJ, Lee J, Lee CS, Kang MJ, Kim DH. Enzymatic C-demethylation of 1-[2-(5-tert-butyl-[1,3,4] oxadiazole-2-carbonyl)-4-fluoro-pyrrolidin-1-yl]-2-(2-hy-droxy-1,1-dimethyl-ethylamino)-ethanone(LC15-0133) in rat liver microsomes. Drug Metab Dispos. 2008 Mar;36(3):485-9.
  43. 43Lee SK, Jun IH, Yoo HH, Kim JH, Seo YM, Kang MJ, Lee SH, Jeong TC, Kim DH. Characterization of vitro metabolites of deoxypodophyllotoxin in human and rat liver microsomes using liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2008;22(1):52-8.
  44. 44Islam NM, Yoo HH, Lee MW, Dong MS, Park YI, Jeong HS, Kim DH. Simultaneous quantitation of five flavonoid glycosides in Herba Epimedii by high-performance liquid chromatography-tan-dem mass spectrometry. Phytochem Anal. 2008 Jan-Feb;19(1):71-7.
  45. 45Yoo HH*, Lee M, Chung HJ, Lee SK, Kim DH. Effects of diosmin, a flavonoid glycoside in citrus fruits, on P-glycoprotein-mediated drug efflux in human intestinal Caco-2 cells. J Agric Food Chem. 2007 Sep 5;55(18):7620-5.
  46. 46Son JH, Yoo HH, Kim DH. Activation of de novo synthetic pathway of ceramides is responsible for the initiation of hydrogen peroxide-induced apoptosis in HL-60 cells. J Toxicol Environ Health A. 2007 Aug;70(15-16):1310-8.
  47. 47Yoo HH, Kim NS, Im GJ, Kim DH. Pharmacokinetics and tissue distribution of a novel PDE5 inhibitor, SK-3530, in rats. Acta Pharmacol Sin. 2007 Aug;28(8):1247-53.
  48. 48Yoo HH, Lee MW, Kim Yc, Yun CH, Kim DH. Mechanism-based inactivation of cytochrome P450 2A6 by decursinol angelate isolated from Angelica Gigas. Drug Metab Dispos. 2007 Oct;35(10):1759-65.
  49. 49Yoo HH, Park JH, Kwon SW. In vitro cytotoxic activity of some Korean medicinal plants on human. Cancer cell lines: enhancement in cytotoxicity by heat processing. Phytother Res. 2007 Sep;21(9):900-3.
  50. 50Yoo HH, Lee M, Lee MW, Lim SY, Shin J, Kim DH. Effects of Schisandra lignans on P-glycopro-tein-mediated drug efflux in human intestinal Caco-2. Planta Med. 2007 May;73(5): 444-50.
  51. 51Piao XL, Park JH, Cui J, Kim DH, Yoo HH*. Development of gas chromatographic/mass spec-trometry-pattern recognition method for the quality control of Korean Angelica. J Pharm Biomed Anal. 2007 Sep 3;44(5):1163-7.
  52. 52Kim NS, Yoo HH, Lee MW, Kim HS, Kim DH. Disposition and metabolism of (2S,3S,4R)-N”-cy-ano-N-(6-amino-3,4-dihydro-3- hydroxyl-2-methyl-2-dimethoxy methyl-2H-benz-opyran-4-yl)-N’-benzylguanidine, a novel neuroprotective agent for ischemia-reperfusion damage, in rats. Xenobiotica. 2007 May;37(5):534-48.
  53. 53Kang KS, Kim HY, Baek SH, Yoo HH, Park JH, Yokozawa T. Study on the hydroxyl radical scav-enging activity changes of ginseng and ginsenoside-Rb2 by heat processing. Biol Pharm Bull. 2007 Apr;30(4):724-8.
  54. 54Lee J, Yoo HH, Rhim KJ, Sohn DR, Kim DH. Metabolism and excretion of 5-ethyl-2-{5-[4-(2-hy-droxyethyl)piperazine-1-sulfon-yl]-2-propoxyphenyl}-7-propyl-3,5-dihydropyrrolo[3,2-d]-pyrimidin-4-one (SK3530) in rats. Rapid Commun Mass Spectrom. 2007;21(7):1139-49.
  55. 55Cho EJ, Lee YA, Yoo HH, Yokozawa T. Protective effects of broccoli (Brassica oleracea) against oxidative damage in vitro and in vivo. J Nutr Sci Vitaminol (Tokyo). 2006 Dec;52(6):437-44.
  56. 56Yoo HH, Park JH, Kwon SW. An anti-estrogenic lignin glycoside, tracheloside, from seeds of Carthamus tinctorius. Biosci Biotechnol Biochem. 2006 Nov;70(11):2783-5.
  57. 57Piao XL, Yoo HH, Kim HY, Kang Tl, Hwang GS, Parkd JH. Estrogenic activity of fuanocoumarins isolated from Angelica dahurica. Arch Pharm Res. 2006 Sep;29(9):741-5.
  58. 58Yoo HH, Son J, Kim DH. Liquid chromatography-tandem mass spectrometric determination of ceramides and related lipid species in cellular extracts. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Nov 7;843(2)327-33.
  59. 59Yoo HH, Son J, Lee J, Kim NS, Shin M, Kang MJ, Kim DH. The metabolism and excretion of 2-methylaminoethoxycarbonyl-4,4’-dimethoxy-5,6,5’6’-dimethyl- enedioxybiphenyl-2’-carboxylic acid (DDB-S) in rats and human. Rapid Commun Mass Spec-trom. 2006;20(13):1981-8.
  60. 60Yoo HH, Kwon SW, Park JH, The cytotoxic saponin from heat-processed Achyranthes fauriei roots. Biol Pharm Bull. 2006 May;29(5):1053-5.
  61. 61Yoo HH, Yokozawa T, Satoh A, Kang KS, Kim HY. Effects of ginseng on the proliferation of human lung fibroblasts. Am J Chin Med. 2006;34(1):137-46.
  62. 62Lee J, Yoo BC, Lee HS, Yoo HW, Yoo HH, Kang Mj, Kim DH. Rapid quantitative determination of
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